Student research projects

Showing all student projects.

Research projects
Targeting Wnt/β-cateinin epigenomics for colorectal cancer treatment
Research area: colorectal cancer
Supervisor: Dr Chunhua (Nick) Wan
Suitability: PhD/Doctorate, Honours, Masters
Targeting ubiquitination signalling as a novel strategy against colorectal cancer
Research area: colorectal cancer
Supervisor: Dr Chunhua (Nick) Wan
Suitability: PhD/Doctorate, Honours, Masters
Functional Annotation of the tumour variants of unknown significance
Research area: bioinformatics
Supervisor: Dr Claire Xin Sun
Suitability: PhD/Doctorate, Honours, Masters
Identifying Novel Targets in Paediatric High Grade Glioma
Research area: paediatric HGG
Supervisor: Dr Yichen Zhou
Suitability: PhD/Doctorate, Honours, Masters
Pulmonary hypertension in our smallest babies – determining the optimal treatment
Research area: fetal growth restriction
Supervisor: Dr Beth Allison
Suitability: PhD/Doctorate, Honours
Making better mRNA therapeutics
Research area: mRNA vaccines
Supervisor: Associate Professor Michael Gantier
Suitability: PhD/Doctorate, Honours, Masters
Creating a new generation of adjuvants for vaccine and cancer immunotherapy
Research area: innate immunity
Supervisor: Associate Professor Michael Gantier
Suitability: PhD/Doctorate, Honours, Masters
Understanding how ADAR1 mutations cause Aicardi-Goutière’s Syndrome
Research area: RNA modification, innate immune, genetics, rare disease
Supervisor: Professor Carl Walkley
Suitability: PhD/Doctorate, Masters
Mapping endogenous ADAR1 expression in vivo.
Research area: RNA modification, genetics
Supervisor: Professor Carl Walkley
Suitability: Honours, Masters
Understanding and improving outcomes for a rare childhood cancer syndrome.
Research area: rare disease, cancer, genetics
Supervisor: Professor Carl Walkley
Suitability: PhD/Doctorate, Honours, Masters
Improving functional deficits associated with fetal growth restriction
Research area: fetal growth restriction
Supervisor: Professor Suzanne Miller
Suitability: PhD/Doctorate, Honours
How are male and female brains different?
Research area: sex differences
Supervisor: Professor Vincent Harley
Suitability: PhD/Doctorate, Honours, Masters
Investigating the robustness of claims of sex differences in disease
Research area: sex differences
Supervisor: Professor Vincent Harley
Suitability: PhD/Doctorate, Honours, Masters
Sex differences in common diseases and drug responses
Research area: sex differences
Supervisor: Professor Vincent Harley
Suitability: PhD/Doctorate, Honours, Masters
Role of estrogen receptor beta in gonadal development and Parkinson’s disease
Research area: Parkinson's disease
Supervisor: Professor Vincent Harley
Suitability: PhD/Doctorate, Honours, Masters
SRY: A risk factor for Parkinson’s disease in males
Research area: Parkinson's disease
Supervisor: Professor Vincent Harley
Suitability: PhD/Doctorate, Honours, Masters
The biological basis of gender identity
Research area: gender identity
Supervisor: Professor Vincent Harley
Suitability: PhD/Doctorate, Honours
FGF9 signalling and sex reversal
Research area: sex determination
Supervisor: Professor Vincent Harley
Suitability: PhD/Doctorate, Honours, Masters
Identifying the genes responsible for intersex conditions
Research area: sex determination
Supervisor: Professor Vincent Harley
Suitability: PhD/Doctorate, Honours
ATR-X syndrome and gonadal development
Research area: sex determination
Supervisor: Professor Vincent Harley
Suitability: PhD/Doctorate, Honours, Masters
Characterisation of novel gonadal targets of Sox9
Research area: sex determination
Supervisor: Professor Vincent Harley
Suitability: PhD/Doctorate, Honours, Masters
Role of XIAP in endocrine cancer (ovarian and thyroid)
Research area: thyroid cancer
Supervisor: Associate Professor Simon Chu
Suitability: PhD/Doctorate, Honours
Molecular pathogenesis of granulosa cell tumours of the ovary
Research area: ovarian cancer
Supervisor: Associate Professor Simon Chu
Suitability: PhD/Doctorate, Honours
Resistant hypertension in primary care – how many have primary aldosteronism?
Research area: primary aldosteronism
Supervisor: Associate Professor Jun Yang
Suitability: PhD/Doctorate, Honours
Primary aldosteronism in pregnancy and beyond
Research area: primary aldosteronism
Supervisor: Associate Professor Jun Yang
Suitability: PhD/Doctorate, Honours, Masters
Impact of ethnicity on the prevalence and aetiology of hypertension
Research area: hypertension
Supervisor: Associate Professor Jun Yang
Suitability: PhD/Doctorate, Masters
Identification of novel transcriptomic markers of PA
Research area: primary aldosteronism
Supervisor: Associate Professor Jun Yang
Suitability: PhD/Doctorate, Honours, Masters
Evaluating the cost-effectiveness of different strategies for the diagnosis and management of primary aldosteronism
Research area: primary aldosteronism
Supervisor: Associate Professor Jun Yang
Suitability: PhD/Doctorate, Masters
Evaluating barriers to the detection of primary aldosteronism
Research area: primary aldosteronism
Supervisor: Associate Professor Jun Yang
Suitability: PhD/Doctorate, Honours, Masters
Establish a national PA registry to enable comprehensive data collection
Research area: primary aldosteronism
Supervisor: Associate Professor Jun Yang
Suitability: PhD/Doctorate, Honours, Masters
Impacts of epigenomic drugs on female reproductive health
Research area: Womens' health
Supervisor: Associate Professor Patrick Western
Suitability: PhD/Doctorate, Honours, Masters
Characterisation of a novel interferon in the pathogenesis and treatment of endometriosis
Research area: endometriosis
Supervisor: Dr Fiona Cousins
Suitability: PhD/Doctorate, Honours, Masters
Developing 3D brain organoids to model perinatal brain injury
Research area: newborn health
Supervisor: Dr Courtney McDonald
Suitability: PhD/Doctorate, Honours
Is neural stem cell therapy safe and feasible in a neonate?
Research area: cerebral palsy, newborn health
Supervisor: Dr Courtney McDonald
Suitability: PhD/Doctorate, Honours
Neural stem cell therapy for preterm brain injury
Research area: cerebral palsy, preterm birth
Supervisor: Dr Courtney McDonald
Suitability: PhD/Doctorate, Honours
Optimising a model of preterm brain injury in the neonatal rat
Research area: cerebral palsy, preterm birth
Supervisor: Dr Courtney McDonald
Suitability: PhD/Doctorate, Honours
Transition to life after birth
Research area: newborn health
Supervisor: Dr Kelly Crossley
Suitability: PhD/Doctorate, Honours
Reducing the risk of pulmonary hypertension in infants with a congenital diaphragmatic hernia.
Research area: newborn health
Supervisor: Dr Kelly Crossley
Suitability: PhD/Doctorate, Honours
Extracellular vesicles in endometriosis
Research area: Endometriosis
Supervisor: Dr Thomas Tapmeier
Suitability: PhD/Doctorate, Honours, Masters
Testing Novel Therapies for Neonatal Seizures
Research area: newborn health
Supervisor: Dr Tamara Yawno
Suitability: Honours, Masters
Mitochondrial protein interactions that cause dysregulation and disease
Research area: mitochondria
Supervisor: Dr Daniel Garama
Suitability: PhD/Doctorate, Honours, Masters
Is interferon β a friend or foe?
Research area: interferon
Supervisor: Dr Daniel Garama
Suitability: PhD/Doctorate, Honours, Masters
How do proteins enter the mitochondria and cause dysregulation?
Research area: mitochondria
Supervisor: Dr Daniel Garama
Suitability: PhD/Doctorate, Honours
Precision Medicine for Childhood Brain Cancer
Research area: precision therapy
Supervisor: Professor Ron Firestein
Suitability: PhD/Doctorate, Honours, Masters
Improving the transition at birth in asphyxiated infants
Research area: preterm birth, newborn health
Supervisor: Professor Graeme Polglase
Suitability: PhD/Doctorate, Honours
Targeting IL-1β for prevention of inflammation-induced brain injury in premature infants
Research area: preterm birth, inflammation
Supervisor: Dr Robert Galinsky
Suitability: PhD/Doctorate, Honours, Masters
The First In Vivo Exploration of Interleukin 38
Research area: inflammation
Supervisor: Professor Marcel Nold
Suitability: PhD/Doctorate, Honours
Exploring a new frontier: The immune system of the premature infant, its interplay with the microbiome, and their relevance in the pathophysiology of major diseases of prematurity
Research area: newborn health
Supervisor: Professor Marcel Nold
Suitability: PhD/Doctorate, Honours
Novel Anti-inflammatory Approaches for Currently Untreatable Diseases of the Preterm Baby: Human specimen analysis and animal Models of Bronchopulmonary Dysplasia and Necrotising Enterocolitis
Research area: bronchopulmonary dysplasia (BPD), necrotising enterocolitis (NEC)
Supervisor: Professor Claudia Nold
Suitability: Honours, Masters
Molecular Characterisation of Regulation and Mechanism of Action of the Anti-inflammatory Cytokine Interleukin 37
Research area: inflammation
Supervisor: Professor Claudia Nold
Suitability: PhD/Doctorate, Honours, Masters
The Role of IL37 in the pathogenesis of inflammatory bowel disease
Research area: inflammatory bowel disease, inflammation
Supervisor: Professor Claudia Nold
Suitability: PhD/Doctorate, Honours
Analysing the effects of a novel anti-inflammatory approach for currently untreatable diseases of the preterm baby using data from Anakinra Pilot, the first clinical trial of its kind
Research area: bronchopulmonary dysplasia, necrotising enterocolitis
Supervisor: Professor Marcel Nold
Suitability: PhD/Doctorate, Honours
Closing the gaps – establishing pediatric reference intervals of pro- and anti-inflammatory cytokines
Research area: newborn health, inflammation
Supervisor: Professor Marcel Nold
Suitability: PhD/Doctorate, Honours
Baby microbiome: Investigating the human neonatal lung and gut microbiome and its impact on health and disease
Research area: newborn health, inflammation
Supervisor: Professor Marcel Nold
Suitability: PhD/Doctorate, Honours
Deciphering Immune Response to Bioengineered Meshes
Research area: pelvic organ prolapse
Supervisor: Dr Shayanti Mukherjee
Suitability: PhD/Doctorate, Honours, Masters
Vaginal Stem Cells: the missing link to vaginal reconstruction
Research area: Reproductive Health
Supervisor: Professor Caroline Gargett
Suitability: PhD/Doctorate, Honours, Masters
Trialling novel glucocorticoids to reduce lung diseases of preterm birth
Research area: preterm birth
Supervisor: Associate Professor Megan Wallace
Suitability: PhD/Doctorate, Honours
Exploring the morphometric properties and immunobiology of Human Fascia Lata as a biological graft in pelvic reconstructive surgery
Research area: pelvic organ prolapse
Supervisor: Dr Shayanti Mukherjee
Suitability: PhD/Doctorate, Honours, Masters
Characterising novel targets for the treatment of endometriosis
Research area: endometrosis
Supervisor: Professor Caroline Gargett
Suitability: PhD/Doctorate, Honours, Masters
Are endometrial mesenchymal stem cells a better efficacious and safer blood-compatible MSC source?
Research area: Endometriosis
Supervisor: Dr Shanti Gurung
Suitability: PhD/Doctorate, Honours
Harnessing the uterine fluid-derived antimicrobial peptides in the fight against endometriosis
Research area: endometriosis
Supervisor: Dr Shanti Gurung
Suitability: PhD/Doctorate, Honours, Masters
Improving the Engagement and Participation of Multicultural Women in Perinatal Clinical Trials
Research area: Stillbirth
Supervisor: Dr Miranda Davies-Tuck
Suitability: PhD/Doctorate, Masters
Modulating gastrointestinal microbiota stimulation of the innate immune system
Research area: gastrointestinal microbiota
Supervisor: Associate Professor Samuel Forster
Suitability: PhD/Doctorate, Honours
High Resolution Computational Analysis of the Gastrointestinal Microbiota
Research area: computational biology
Supervisor: Associate Professor Samuel Forster
Suitability: PhD/Doctorate, Honours
Discovery of antibiotic resistance gene dispersal networks in the human gastrointestinal microbiota
Research area: antibiotic resistance
Supervisor: Associate Professor Samuel Forster
Suitability: PhD/Doctorate, Honours
Characterization of human microbiota diversity across the Australian community
Research area: microbiota, microbiology
Supervisor: Associate Professor Samuel Forster
Suitability: PhD/Doctorate, Honours
Blocking harmful lung damage during acute exacerbations of chronic obstructive pulmonary disease caused by infections
Research area: virus, infection
Supervisor: Professor Philip Bardin
Suitability: PhD/Doctorate
Novel host-directed therapies for severe influenza virus infections
Research area: virus, therapies
Supervisor: Associate Professor Michelle Tate
Suitability: PhD/Doctorate, Honours
Characterization of microbiota composition in paediatric inflammatory bowel disease
Research area: microbiota, microbiome
Supervisor: Associate Professor Samuel Forster
Suitability: PhD/Doctorate, Honours, Masters
Mechanisms of mucosal damage and repair during bacterial gut infection
Research area: microbiology, inflammation
Supervisor: Professor Elizabeth Hartland
Suitability: PhD/Doctorate, Honours, Masters
Intracellular bacterial pathogens and cell intrinsic immunity
Research area: microbiology, legionella
Supervisor: Professor Elizabeth Hartland
Suitability: PhD/Doctorate, Honours, Masters
Role of membrane damaging effector proteins in innate immune cell-mediated tissue injury
Research area: cell death
Supervisor: Associate Professor Kate Lawlor
Suitability: PhD/Doctorate, Honours, Masters
Defining regulators of cell death and inflammasome activation
Research area: cell death
Supervisor: Associate Professor Kate Lawlor
Suitability: PhD/Doctorate, Honours, Masters
Understanding the role of cell death during severe influenza virus infections
Research area: influenza, virus
Supervisor: Associate Professor Michelle Tate
Suitability: PhD/Doctorate, Honours
The role of the innate immune system in preventing stomach cancer during chronic Helicobacter pylori infection
Research area: innate immunity
Supervisor: Professor Richard Ferrero
Suitability: Honours
Development of a vaccine to prevent stomach cancer using genetically modified bacterial membrane vesicles
Research area: cancer, vaccine
Supervisor: Professor Richard Ferrero
Suitability: PhD/Doctorate, Honours, Masters
Defining the role of a novel NLR protein in stomach B cell lymphoma associated with chronic Helicobacter infection
Research area: innate immunity
Supervisor: Professor Richard Ferrero
Suitability: PhD/Doctorate, Honours, Masters
Characterisation of the immunomodulatory and oncogenic properties of bacterial extracellular vesicles
Research area: innate immunity
Supervisor: Professor Richard Ferrero
Suitability: PhD/Doctorate, Honours, Masters
The role of Mediator kinases during lung homeostasis and disease
Research area: homeostasis
Supervisor: Dr Marius Dannappel
Suitability: PhD/Doctorate, Honours, Masters
Targeting Mediator kinases to improve the efficacy of immunotherapies in colorectal cancer
Research area: colorectal cancer
Supervisor: Dr Marius Dannappel
Suitability: PhD/Doctorate, Honours, Masters
Linking gene expression and genome organisation
Research area: organoids
Supervisor: Dr Marius Dannappel
Suitability: PhD/Doctorate, Honours, Masters
Targeting purine and pyrimidine synthesis to treat Small Cell Lung Cancer
Research area: lung cancer
Supervisor: Associate Professor Daniel Gough
Suitability: Honours, Masters
Spatial transcriptomic analysis of the lung cancer microenvironment
Research area: spatial transcriptomics
Supervisor: Associate Professor Daniel Gough
Suitability: Honours, Masters
Leveraging the innate immune system to improve lung cancer treatments
Research area: lung cancer
Supervisor: Associate Professor Daniel Gough
Suitability: PhD/Doctorate
Leveraging lung organoid models to improve lung cancer treatments
Research area: lung cancer
Supervisor: Associate Professor Daniel Gough
Suitability: PhD/Doctorate, Honours, Masters
Functional genomic screening to identify novel approaches to overcome drug resistance in Small Cell Lung Cancer
Research area: lung cancer
Supervisor: Associate Professor Daniel Gough
Suitability: PhD/Doctorate
Defining drivers of metastatic lung cancer
Research area: lung cancer
Supervisor: Associate Professor Daniel Gough
Suitability: PhD/Doctorate
Understanding cancer resistance to chemotherapy
Research area: drug targets
Supervisor: Professor Ron Firestein
Suitability: PhD/Doctorate, Honours, Masters
Transcriptional regulators as cancer targets: new models and therapeutic approaches
Research area: transcription
Supervisor: Professor Ron Firestein
Suitability: PhD/Doctorate, Honours, Masters
Functional genomic screens to identify new therapeutic targets for bowel cancer
Research area: genomics
Supervisor: Professor Ron Firestein
Suitability: PhD/Doctorate, Honours, Masters
Development of new 3-dimensional models of cancer to model drug resistance and develop new cancer treatment
Research area: colon cancer
Supervisor: Professor Ron Firestein
Suitability: PhD/Doctorate, Honours, Masters
Novel innate immune variants causing autoinflammatory disease
Research area: autoinflammatory disease
Supervisor: Professor Seth Masters
Suitability: PhD/Doctorate
Is creatine the nutritional key to boosting uterine receptivity and successful pregnancy?
Research area: Fertility, Preterm Birth
Supervisor: Dr Stacey Ellery
Suitability: PhD/Doctorate
Investigating cerebral creatine metabolism during neurodevelopment and its capacity to prevent neuropathology
Research area: Preterm birth
Supervisor: Dr Stacey Ellery
Suitability: PhD/Doctorate
Modelling childhood leukaemia for the development of new and improved therapeutic approaches
Research area: leukaemia
Supervisor: Dr Catherine Carmichael
Suitability: PhD/Doctorate, Honours, Masters
Genetic modelling of Acute Erythroleukaemia
Research area: erythroleukaemia
Supervisor: Dr Catherine Carmichael
Suitability: PhD/Doctorate, Honours, Masters
Elucidating the role of EMT modulators in Acute Leukaemia
Research area: leukaemia
Supervisor: Dr Catherine Carmichael
Suitability: PhD/Doctorate, Honours, Masters
Revolutionizing Breast Cancer Immunotherapy: Unveiling Novel Vaccine Targets
Research area: immunotherapy
Supervisor: Dr Pouya Faridi
Suitability: PhD/Doctorate, Honours, Masters
Illuminating Disease Frontiers – Advancing Biomarker Discovery with Soluble HLA Immunopeptidomics and Olink Proteomics
Research area: biomarker discovery
Supervisor: Dr Pouya Faridi
Suitability: PhD/Doctorate, Honours, Masters
Development of combination therapies for childhood cancers
Research area: childhood cancer
Supervisor: Dr Pouya Faridi
Suitability: PhD/Doctorate, Honours, Masters
Immune Enigma Unveiled – Pioneering Bioinformatic Pipelines for Non-Canonical HLA-Bound Peptide Exploration
Research area: immunology, bioinformatics
Supervisor: Dr Pouya Faridi
Suitability: PhD/Doctorate, Honours, Masters
Impact of impaired immune function in haemoglobin disorders
Research area: thalassaemia
Supervisor: Dr Jim Vadolas
Suitability: PhD/Doctorate, Honours, Masters
Harnessing RNA interference in gene therapy vectors for β-thalassaemia
Research area: gene therapy
Supervisor: Dr Jim Vadolas
Suitability: PhD/Doctorate, Honours, Masters
Epigenetic modifications of the human β-globin locus: new therapeutic targets for haemoglobin disorders
Research area: epigenetics
Supervisor: Dr Jim Vadolas
Suitability: PhD/Doctorate, Honours, Masters
Identification of molecular prognostic and therapy resistance signatures in paediatric sarcomas
Research area: sarcomas
Supervisor: Associate Professor Jason Cain
Suitability: PhD/Doctorate, Honours
Exploiting Epigenetic Dysregulation in SWI/SNF-Deficient Solid Tumours
Research area: epigenetics
Supervisor: Associate Professor Jason Cain
Suitability: PhD/Doctorate, Honours
Defining the mechanisms of chemotherapy resistance in childhood and adolescent osteosarcoma
Research area: osteosarcoma
Supervisor: Associate Professor Jason Cain
Suitability: PhD/Doctorate, Honours
Preventing disease recurrence and increasing disease free survival rates for ovarian cancer patients
Research area: ovarian cancer
Supervisor: Dr Maree Bilandzic
Suitability: Honours
Mechanisms of ovarian cancer metastasis- characterizing molecules expressed during early cancer invasion
Research area: ovarian cancer
Supervisor: Dr Maree Bilandzic
Suitability: Honours
Development of face perception in preterm infants (The BabyFace Study)
Research area: Preterm Birth
Supervisor: Associate Professor Flora Wong
Suitability: PhD/Doctorate, Honours
Regulation of the germline and fetal organ growth by environmental cues
Research area: Infertility, epigenetics
Supervisor: Professor Kate Loveland
Suitability: Honours, Masters
An Importin protein that mediates growth factor signalling and pathway crosstalk: Its roles in spermatogenesis
Research area: Spermatogenesis, cell signalling
Supervisor: Professor Kate Loveland
Suitability: Honours, Masters
Defining the epigenetic origins of maternally inherited disease
Research area: Offspring health
Supervisor: Associate Professor Patrick Western
Suitability: PhD/Doctorate, Honours
Spermatogonial stem cells and male fertility
Research area: Male fertility
Supervisor: Associate Professor Robin Hobbs
Suitability: PhD/Doctorate, Honours, Masters
Preservation and regeneration of male fertility by germline stem cells
Research area: Male fertility
Supervisor: Associate Professor Robin Hobbs
Suitability: PhD/Doctorate, Honours, Masters
Discovering therapies to prevent inflammatory diseases of the male reproductive tract and infertility
Research area: Inflammation-induced infertility
Supervisor: Dr Rukmali Wijayarathna
Suitability: PhD/Doctorate, Honours, Masters