Professor Peter Fuller AM, MBBS FRACP PhD
- Centre Head, Centre for Endocrinology and Metabolism
- Research Group Head, Steroid Receptor Biology
Steroid hormones play a critical role in a wide range of conditions including heart disease and endocrine (hormone) cancers. By investigating how steroid hormones maintain health and initiate disease, my goals are to find new ways to diagnose and treat these diseases.
Areas of interest
Professor Fuller is a physician-scientist who leads the Centre for Endocrinology and Metabolism and is Head of the Endocrinology Unit at Monash Health, Victoria’s largest health service.
An endocrinologist and nuclear receptor biologist in the fields of cardiovascular disease and cancer, Prof Fuller’s principal areas of research are steroid receptor biology, and the molecular aetiology, pathogenesis and treatment of endocrine cancers.
Professor Fuller has made substantive contributions to the understanding of the steroid hormone receptor for aldosterone, the mineralocorticoid receptor (MR), particularly with respect to ligand-binding, gene expression, structure-function relationships, and the mechanisms of signalling. Professor Fuller’s Research group has also successfully applied novel in vivo models to the study of the cell-specific roles of the MR in cardiovascular disease.
The impact of Professor Fuller’s research has primarily been in its contribution to knowledge of the genetics, structural biology, molecular mechanisms and function, both cellular and integrated, of MR in normal physiology and in disease. This knowledge has contributed to the development of novel MR antagonists (MRA), and to the rationale for the use of MRA.
Professor Fuller has received more than $7.8M in grant funding over the last five years from both national and State government agencies (NHMRC and Medical Research Future Fund), as well as from national and international philanthropic funding bodies.
In 2015, Professor Fuller was made a Member in the General Division of the Order of Australia (AM) for his services to endocrinology.