Professor Richard Ferrero

Tran LS, Ying L, D’Costa K, Wray-McCann G, Kerr G, Le L, Allison CC, Ferrand J, Chaudhry, H, Emery J, De Paoli A, Colon N, Creed S, Kaparakis-Liaskos M, Como J, Dowling JK, Johanesen PA, Kufer TA, Pedersen JS, Mansell A, Philpott DJ, Elgass K, Abud HE, Nachbur U, Croker BA, Masters SL, Ferrero RL. (2023) NOD1 mediates interleukin-18 processing in epithelial cells responding to Helicobacter pylori infection in mice. Nat Commun 14, 3804.

Ying L, Liu P, Ding Z, Wray-McCann G, Emery J, Colon N, Le LHM, Xu P, Yu L, Philpott DJ, Tu , Cheah DMZ, Cheng CL, Lim ST, Ong CK, Ferrero RL. (2023) Anti-CD40L therapy prevents the formation of precursor lesions to gastric B-cell MALT lymphoma in a mouse model. J Pathol 259, 402-414.

Chonwerawong M, Ferrand J, Chaudhry HM, Higgins C, Tran LS, Lim SS, Walker MM, Bhathal P, Dev A, Moore GT, Sievert W, Jenkins BJ, D’Elios MM, Philpott DJ, Kufer TA, Ferrero RL. (2020) Innate immune molecule NLRC5 protects mice from Helicobacter-induced formation of gastric lymphoid tissue. Gastroenterol 150, 169-182.

Bitto NJ, Baker PJ, Dowling JK, DePaoli A, Tran LS, Leung PL, Stacey KJ, Mansell A, Masters SL, Ferrero RL. (2018) Pseudomonas aeruginosa membrane vesicles activate the non-canonical inflammasome in human macrophages through caspase-5. Immunol Cell Biol 10, 1120-1130.

Bitto NJ, Chapman R, Pidot S, Costin A, Lo C, Choi J, D’Cruze T, Reynolds EC, Dashper SG, Turnbull L, Whitchurch CB, Stinear TP, Stacey KJ, Ferrero RL. (2017) Bacterial membrane vesicles transport their DNA cargo to the nucleus of host Sci Rep 7:7072. DOI:10.1038/s41598-017-07288-4

Kaparakis-Liaskos, M., Ferrero, R. L. (2015) Immune modulation by bacterial outer membrane vesicles. Nat Rev Immunol 15: 376-387.

Irving AT, Mimuro H, Kufer TA, Lo C, Wheeler R, Turner LJ, Thomas BJ, Malosse C, Gantier MP, Casillas LN, Votta BJ, Bertin J, Boneca IG, Sasakawa C, Philpott DJ, Ferrero RL, Kaparakis-Liaskos M (2014) The immune receptor NOD1 and kinase RIP2 interact with bacterial peptidoglycan on early endosomes to promote autophagy and inflammatory signaling. Cell Host Microbe 15:623-635.

Allison CC, Ferrand J, McLeod L, Hassan M, Kaparakis-Liaskos M, Grubman A, Bhathal PS, Dev A, Sievert W, Jenkins BJ, Ferrero RL (2013) Nucleotide oligomerization domain 1 enhances IFN-gamma signaling in gastric epithelial cells during Helicobacter pylori infection and exacerbates disease severity. J Immunol 190:3706-3715.

Kaparakis M, Turnbull L, Carneiro L, Firth S, Coleman HA, Parkington HC, Le Bourhis L, Karrar A, Viala J, Mak J, Hutton ML, Davies JK, Crack PJ, Hertzog PJ, Philpott DJ, Girardin SE, Whitchurch CB, Ferrero RL (2010) Bacterial membrane vesicles deliver peptidoglycan to NOD1 in epithelial cells. Cell Microbiol 12:372-385.

Grubman A, Phillips A, Thibonnier M, Kaparakis-Liaskos M, Johnson C, Thiberge JM, Radcliff FJ, Ecobichon C, Labigne A, de Reuse H, Mendz GL, Ferrero RL (2010) Vitamin B6 is required for full motility and virulence in Helicobacter pylori. MBio 1:e00112-10.

Fritz JH, Ferrero RL, Philpott DJ, Girardin SE. (2006) Nod-like proteins in immunity, inflammation and disease. Nat Rev Immunol 7, 1250-1257.

Viala J, Chaput C, Boneca IG, Cardona A, Girardin SE, Moran AP, Athman R, Mémet S, Huerre MR, Coyle AJ, DiStefano PS, Sansonetti PJ, Labigne A, Bertin J, Philpott DJ, Ferrero RL (2004) Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island. Nat Immunol 5:1166-1174.