Professor Seth Masters is a member of the Centre for Innate Immunity and Infectious Diseases.

Professor Seth Masters, Centre Head of the Centre for Innate Immunity and Infectious Diseases


Professor Seth Masters was appointed as the Head of the Centre for Innate Immunity and Infectious Diseases at Hudson Institute in February 2024. A particular focus of his research is a family of innate immune receptors known as Nod-like receptors (NLRs).

Professor Masters uncovered the genetic basis for several autoinflammatory diseases and continues to manage the associated Australian Registry, AADRY. Mechanistically this work has defined the role of inflammasome sensors such as NLRP1 and NLRC4 in IBD, and the cGAS/STING pathway in ALS.

An expert in genetic disorders that trigger inflammatory diseases, Professor Masters has spent the past 12 years as Head of the Inflammasomes and Autoinflammatory Disease Laboratory at the Walter and Eliza Hall Institute (WEHI). Professor Masters’ achievements and affiliations include a joint appointment at the Guangzhou Women’s and Children’s Hospital (China), as well as being a Fellow of the HHMI-Wellcome Trust, the Viertel Foundation and the National Health and Medical Research Council (NHMRC).

He completed his BSc (Hons) and PhD at the University of Melbourne and more recently took on roles as VP of Discovery Biology at NRG Therapeutics and as a Scientific Advisor for Odyssey Therapeutics.

READ MORE | Hudson Institute welcomes inflammation specialist as new Centre Head


Awards and fellowships

Publication highlights