Centre for Reproductive Health
Centre Head
Hudson Institute of Medical Research is internationally recognised for its outstanding research into reproduction, which spans more than 40 years. The Centre for Reproductive Health’s current reproductive health research program is strongly based in both basic and translational science. Reproductive Health is now a key global challenge, with impacts of the environment and changes in societies strongly impacting not only on both male and female reproduction but also on the long-term health of their offspring. The latter detrimental changes are established both in the sperm and egg, and during early development of the conceptus.
With a rapidly increasing world population, the need for new contraceptive options has never been greater. Furthermore, translation of advances in reproductive sciences also impacts on cancer biology, animal food production, and conservation of endangered species. In addition, proteins involved in the regulation of reproduction also have wider actions influencing inflammation and tissue repair in a wide variety of organs.
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CRH is the proud sponsor of Reproductive Health Australia, the peak advocacy body promoting research and research translation in reproductive biology across Australia.
Professor Kate Loveland receives International Scientist Award
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![]() Congratulations Rukmali! Dr Rukmali Wijayarathna, an Early Career Researcher in the Endocrinology and Immunology Lab has won the Anna Steinberger Trainee Merit Award at the 48th Annual Conference of the American Society for Andrology (ASA) held in Boston in April 2023. This highly competitive award is given to a Trainee Member of the Society who presented an original laboratory or clinical research report judged to be most meritorious at the ASA Annual Meeting. The award was for her presentation titled: ‘Interferon epsilon: a novel anti-viral agent in the male reproductive tract’. Dr Wijayarathna’s research showed that Interferon epsilon is expressed in cells that develop into sperm, and protects testes against Zika virus infection, changing our understanding of anti-viral defences in the male reproductive system. This work will ultimately benefit men with fertility defects arising due to virus infections. |
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![]() Congratulations Penny! Penny Whiley, PhD Student, Testis Development and Germ Cell Biology is the winner of the 2021 MHTP PhD Student Symposium with her presentation titled ‘Activin A impacts on germ cell development: new insights into male infertility’, which was held on 6 October 2021. Penny’s supervisors are Prof Kate Loveland and A/Prof Robin Hobbs. |
![]() 3 x germ cells (gonocytes) enriched for stem cell capacity. ‘These cells will likely become spermatogonial stem cells (SSCs), which are essential for maintaining spermatogenesis and sperm production in adult mammals. Immunofluorescence on newborn mouse testis, SALL4 (red fluorescent signal) marks gonocytes, GFRA1 (green fluorescent signal) marks cells with a high stem cell potential, and DNA counterstained with DAPI (blue).’ Penny Whiley , CRH PhD Student |
Key areas of research
- Male Reproductive Health
- Male factor infertility
- Male reproductive cancer
- Immunobiology in male reproductive health
- Reproductive Developmental Biology
- Offspring health
- Environmental exposures
- Molecular Biology of Reproduction
- Germline genetics and epigenetics
- RNA biology