Dr Atul Malhotra, an Honorary Clinical Associate in the Neurodevelopment and Neuroprotection Research Group at Hudson Institute

Associate Professor Atul Malhotra, MBBS, MD, DNB, FRACP, PhD

Associate Professor Atul Malhotra is a Senior Neonatologist at Monash Newborn, Monash Children’s Hospital and Clinician Scientist/ NHMRC fellow in the Department of Paediatrics, Monash University.

His clinical research interests focus on improving respiratory and neurological outcomes of high-risk infants. He has a keen interest in neonatal evidence based medicine, having been involved in a number of large randomised clinical trials and cohort studies. He is passionate about neurodevelopment following high-risk birth and is the Head of the Early Neurodevelopment Clinic at Monash Children’s Hospital.

His basic science interests include understanding and treating brain injury related to high risk perinatal conditions. His basic science PhD was on “Novel strategies for early detection and treatment of fetal growth restriction related brain injury” completed at the Ritchie Centre, Hudson Institute of Medical Research.

He has been instrumental in the translation of preclinical therapies from the laboratory to the clinic, including regenerative cell therapies. He led a world-first trial of placental stem cells for chronic lung disease of prematurity, and is the Principal Investigator of a umbilical cord blood derived cell therapy trial in extremely premature infants (CORD-SaFe), currently recruiting. He is the co-director of the Newborn Cell Therapies Group of School of Clinical Sciences at Monash Health.

One of his other research interests includes medical device innovation/ artificial intelligence. Together with colleagues in the Faculty of Engineering at Monash University, their Biomedical Signal Processing Lab focuses on improving cardio-respiratory monitoring in newborn infants.

He is also passionate about education, and served as the inaugural Co-Chair of Monash Children’s Hospital Simulation Centre. He has been running simulation based education programs in Australia and around the world, and is the co-founder of the global health interprofessional education program, ONE-Sim Education.

Selected publications

  • Aridas JDS, Yawno T, Sutherland AE, Nitsos I, Ditchfield M, Wong FY, Hunt RW, Fahey MC, Malhotra A, Wallace EM, Jenkin G, Miller SL (2018) Systemic and transdermal melatonin administration prevents neuropathology in response to perinatal asphyxia in newborn lambs. J Pineal Res 2018 May; 64(4):e12479.

  • Lim R*, Malhotra A*, Tan JL, Chan ST, Lau S, Zhu D, Mockler JC, Wallace EM (2018) First-in-human administration of allogeneic amnion cells in premature infants with bronchopulmonary dysplasia: a safety study. Stem Cells Transl Med 2018 Sep;7(9):628-635.

  • Malhotra A, Castillo-Melendez M, Allison BJ, Sutherland AE, Nitsos I, Pham Y, Alves de Alencar Rocha AK, Fahey MC, Polglase GR, Jenkin G, Miller SL (2018) Neuropathology as a consequence of neonatal ventilation in premature growth restricted lambs. Am J Physiol Regul Integr Comp Physiol 2018 Dec; 315(6): R1183-1194.

  • Baker EK, Malhotra A, Lim R, Jacobs SE, Hooper SB, Davis PG, Wallace EM (2019) Human amnion cells for the prevention of bronchopulmonary dysplasia. a protocol for a phase 1 dose escalation study. BMJ Open 2019;9:e026265.

  • Malhotra A*, Allison BJ*, Castillo-Melendez M, Jenkin G, Polglase GR, Miller SL (2019) Neonatal morbidities of fetal growth restriction: pathophysiology and impact. Front Endocrinol 2019;10:55.