Neurodevelopment and Neuroprotection

The Neurodevelopment and Neuroprotection research group is embedded within the Fetal and Neonatal Health Neurodevelopment and Brain Injury Theme of The Ritchie Centre. The group provides a focus for experimental and clinical studies directed towards understanding, and inhibiting, the mechanisms that contribute to perinatal brain injury and functional deficits associated with cerebral palsy. We strive towards the implementation of treatments to decrease neonatal brain injury and that can be effectively administered either during pregnancy or in the neonatal period. Such treatments include antioxidants, anti-inflammatory agents, and stem cells obtained from the cord blood and placenta.

Associate Professor Suzie Miller’s group comprises more than 20 members with experts in fetal physiology, neuroscience, stem cells, cardiovascular physiology, clinical obstetrics, neonatology and paediatrics. This group provides a highly-regarded training platform for biomedical and clinical students.

Research Projects

  • Stem cells to reduce perinatal brain injury – fact or fiction?
  • Protecting the intrauterine growth restricted (IUGR) fetal brain with natural neurosteroids.
  • Treating neonatal seizures with ganaxolone
  • Can we modify neurovascular development in the IUGR brain with endothelial progenitor stem cells derived from cord blood?
  • Umbilical cord blood stem cells to improve brain structure and function after severe birth asphyxia, when to administer and how many?
  • Improving newborn wellbeing in a rural Indian community with a simple transdermal patch.
Protect Me Trial

ProtectMe Trial – fetal growth restriction (FGR)

Are you pregnant with a baby with FGR?

This trial looks at the use of melatonin to protect the developing brain of babies with fetal growth restriction (FGR) during pregnancy.

More information >

Research Group