Lupus is a chronic autoimmune disease that sees the body’s immune system attack its own tissues and organs. More common in women than men, it can inflame the skin, blood cells, joints, kidneys, brain, heart, and lungs.

Lupus is difficult to diagnose as its many symptoms may mimic those of other conditions. They may be mild or cause significant disability.

Some people are born with a tendency to develop lupus, but it can be triggered without warning by an infection, some prescription drugs or even sunlight. There is no cure, but treatments can manage the symptoms. 

Types of lupus

Risk factors

Signs, symptoms and diagnosis of lupus

Causes of lupus

Treatment of lupus

Our lupus research

Lupus is a difficult disease to diagnose and treat. Hudson Institute researchers are investigating improved ways to detect lupus, and treatments that may control its triggers and better target its symptoms.

Genetic variants that contribute to lupus

Professor Seth Masters researching Childhood lupusIn this project, Professor Masters and his team are sequencing the DNA of patients with childhood-onset lupus, or related conditions. In some cases, alterations have been found in key innate immune genes which contributed to the development of disease. This specific diagnosis helps understand the reason why some children have developed the disease, and points towards which therapy is likely to be most beneficial for them.


Lead Researcher | Professor Seth Masters

Developing new treatments for lupus

Preventing inflammation caused by lupus

Controlling the triggers that cause lupus

Lupus collaborators

Support for people with Lupus

Hudson Institute scientists cannot provide medical advice.
Find out more about Lupus.

Share this page