Lung cancer

Lung cancer occurs when cells divide in the lungs uncontrollably, causing tumours to grow. This can affect a patient’s breathing and the cancer can spread to other parts of the body.

Lung cancer is the leading cause of cancer deaths in the world and Australia.

What causes lung cancer?

What are the types of lung cancer?

What are lung cancer treatments?

Our lung cancer research

Hudson Institute researchers are working to understand how to prevent, detect and treat lung cancer.

Our teams are making significant progress in identifying an early detection test and new treatment targets for lung cancer patients.

Overcoming platinum resistant small cell lung cancer (SCLC)

Dr Daniel Gough from the STAT Cancer Biology Research Group at Hudson InstituteImproved treatment.  The majority of small cell lung cancer patients are diagnosed with advanced disease, which limits their treatment options to platinum-based chemotherapy. These patients typically respond well, but for a limited time before a drug resistant disease recurs. There is no effective second line therapy, and as a result more than 95 per cent of patients succumb to their disease. Dr Gough’s research is defining the mechanisms that drive platinum resistance to enable more durable responses to this key front-line agent. In addition, his team is identifying new therapies that can treat platinum resistant disease, which will improve the treatment arsenal. Dr. Gough’s laboratory uses combinations of patient derived material, resistant cell lines, pre-clinical mouse models of treatment naïve and platinum resistant disease, functional genomics, proteomics and drug screening technologies.

Team | Associate Professor Daniel Gough, Dr Vinod Ganju, Professor Paul Hertzog

Re-engaging the immune system to kill SCLC

Targeting epigenetic dysregulation in lung cancer

Lung cancer collaborators

Support for people with lung cancer

Hudson Institute scientists cannot provide medical advice.
Find out more about Lung cancer.

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