Transcriptional regulators as cancer targets: new models and therapeutic approaches

Research area

 |  transcription


 |  genetics, genomics, cancer, oncogenes, transcription


 |  PhD/Doctorate, Honours, Masters

Contact supervisors at any time

Professor Ron Firestein

Project description

Transcriptional regulators play a key role in activating oncogenic pathways that impinge on tumour growth, invasion and mestasasis. We study the role of Mediator kinases CDK8/19 as transcriptional regulators in normal tissue homeostasis and cancer (Sooraj et al., Molecular Cell 2022).