Dr Courtney McDonald
We identified that umbilical cord blood cells protect the brain from injury by altering the immune response in the brain and the periphery. We also identified one particular cell type, endothelial progenitor cells which are found in cord blood, that may be a novel cell type that can be used to treat brain injury in babies.
The Ritchie Centre
Neurodevelopment and Neuroprotection group
Journal and article title
This work helps us further understand how UCB can protect the brain and helps us understand how to use these cell for treating Cerebral Palsy. It is also exciting that we have shown that endothelial progenitor cells may be a better option than using whole UCB to treat brain injury.
We now need to understand the long term effects of endothelial progenitor cells for protecting the brain, and confirm that they are better than UCB. This could change the direction of future cell therapies used for cerebral palsy.