Lead researcher
Rebecca Lim
Main finding
Treatment options for patients with end stage liver cirrhosis are incredibly limited. Ultimately, a liver transplant is the only cure. Our preclinical research to date has provided robust data suggesting that allogeneic human amnion epithelial cells (hAECs) can reverse established liver fibrosis and reduce liver inflammation despite ongoing damage. It is with these promising data that we had progressed our research to a Phase 1 clinical trial, where we hope to determine the safety profile of these stem-like cells in patients with compensated liver cirrhosis.
Centre
The Ritchie Centre
Research group
Amnion Cell Biology
Journal and article title
Most surprising
NA
Future implications
NA
Disease/health impact
liver cirrhosis