Lead researcher
Professor Brendan Jenkins
Main finding
This invited review summarises the most recent findings about the interleukin-6 cytokine family in infectious diseases, inflammatory disorders and cancers, and the current strategies (and outcomes) in the clinic to block the actions of these cytokines against these diseases.
Centre
Centre for Innate Immunity & Infectious Diseases
Research group
Cancer and Immune Signalling Laboratory
Journal and article title
Most surprising
The diverse breadth of immune-related responses that these cytokines can regulate, and how they impact on the above disease states.
Future implications
Providing a timely and urgently needed review - to basic and clinical researchers - of the literature on the targeting of these cytokines in the above disease states, as well as perspectives on what the current gaps in knowledge are and how they can be addressed.
Disease/health impact
Inflammation and cancer
