Lead researcher
Mr Majid Alhomrani
Main finding
Cirrhosis is the end-stage of liver fibrosis characterised by replacement of normal liver tissue into scar tissue. The only treatment options available for cirrhosis patients is liver transplantation. Here we provide a robust data suggesting that human amnion epithelial cells (hAECs) derived exosome (cell-free therapy) could reverse established liver fibrosis and reduce liver inflammation despite the ongoing damage.
Centre
Other
Research group
Liver/Gut Inflammation and Fibrosis-SCS and Amnion Cell Biology-TRC
Journal and article title
Most surprising
Exosome derived from hAECs had similar therapeutic effects to hAECs in chronic liver fibrosis. The exosome is a promising cell-free therapy for chronic liver injury.
Future implications
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Disease/health impact
Liver fibrosis